AI Agent Index
ByHeather MacAvelia·Independently reviewed·Published Mar 21, 2026·Updated Sep 30, 2026
Independently verified against live vendor data on Sep 30, 2026.

Systematic review platform for screening references, with duplicate detection, AI screening and collaboration. Free plan; Essential $4.99 and Advanced $8.33 per seat per month billed annually.

How we scored it

Autonomy

3/5

Integrations

4/5

Pricing clarity

4/5

Evidence

4/5

Setup

5/5

The facts

Rayyan is a web and mobile platform for systematic literature reviews, made by Rayyan Systems, Inc. It began as a research project at the Qatar Computing Research Institute, described in a 2016 paper in the journal Systematic Reviews. Rayyan calls itself the number one systematic review platform and says it is used by more than 1 million researchers at more than 30,000 institutions in over 190 countries. It suits students, academic researchers, clinicians and evidence-synthesis teams who screen large numbers of references against inclusion and exclusion criteria. A review in Rayyan runs from importing references through title and abstract screening, full-text screening, data extraction and risk of bias assessment. Duplicate detection is included on every plan, and the Systematic Auto-Resolver clears duplicates automatically on paid plans. AI relevance predictions rank references as reviewers screen, a workbench with more than 15 facets filters the set, and reviewers can work blind, use sampling to split the workload, and screen offline on the iOS and Android apps. Paid plans add PRISMA flow diagrams and AI extraction of PICO data. ResearchPilot, on the institutional plans, adds an AI Reviewer that joins the review team and screens every article against the review's criteria with a reason for each decision, an AI Analyzer that recommends decisions for reviewers to accept, and chat across the articles in a review. A structured Risk of Bias workspace is also new. References are imported from files exported by reference managers and databases, including RIS, BibTeX, EndNote and PubMed formats. The Enterprise plan includes an API and an official Python SDK for reading review data, automating workflows and connecting Rayyan to other systems. Rayyan does not publish MCP documentation. The Free plan allows 3 active reviews, 2 free reviewers and 1 sample, with duplicate detection, AI relevance predictions and limited mobile app use. Essential, per seat, is $4.99/mo billed annually ($59.88 a year), or $8.33 a month billed quarterly, and adds 5 free reviewers, PRISMA diagrams, auto-resolved duplicates and unlimited mobile use. Advanced is $8.33 per seat per month billed annually ($99.99 a year), or $13.33 billed quarterly, and adds 9 active reviews, 10 free reviewers and AI PICO extraction. Business and Academic plans for institutions are $41.67 per license per month billed annually, starting at 5 licenses ($2,500 a year), with ResearchPilot, 250 free reviewers and 50 organization-wide reviews; academic discounts are available. Enterprise is custom-priced and adds SSO, the API and unlimited reviews. Rayyan's trust center shows a HIPAA compliance attestation from May 2026 for plans arranged through sales, a GDPR representative, WCAG 2.2 AA accessibility, and SOC 2 Type II and ISO 27001 engagement letters. Customer data is hosted on AWS in the US, and its AI features use OpenAI models deployed on Microsoft Azure. Rayyan organizes and screens references that a team has already found; it does not search the literature for them. Researchers who want an AI assistant to search and extract from papers can look at Elicit, and those who want deep literature search that follows citation trails can look at Undermind. Researchers who want to see how later papers cite a study can look at Scite.ai, and those who want broad research reports from the web can look at Gemini Deep Research. Current state Q4 2026: Rayyan has launched ResearchPilot and a Risk of Bias workspace and restructured its plans into Free, Essential, Advanced, Business/Academic and Enterprise, billed quarterly or annually. Its HIPAA attestation was published in July 2026. The Android app on Google Play shows 3.6 stars from 240 reviews and more than 100,000 downloads, and Rayyan's G2 profile has no reviews yet.

Pricing

freemium · $4.99/mo annual

View pricing ↗

Segment

b2b

Setup

easy

Verified

Sep 30, 2026

Transparency

Mostly Public

Contract

Monthly or Annual

Data training

Not Disclosed

Human in loop

Required

Capabilities

systematic-reviewliterature-reviewcitationsdata-analysis

Pros & Limitations

Editorial assessment

Pros

  • ✓A usable free plan with duplicate detection and AI relevance predictions, and paid seats from $4.99/mo billed annually.
  • ✓Covers the whole screening workflow in one place: import, duplicates, blind screening, full-text review, data extraction, risk of bias and PRISMA diagrams.
  • ✓Rayyan says it is used by more than 1 million researchers at more than 30,000 institutions, and it offers iOS and Android apps that screen offline.

Limitations

  • –It screens references a team has already gathered; it does not search literature databases for them.
  • –ResearchPilot's AI Reviewer starts on the Business/Academic plan at $2,500 a year for 5 licenses, and the API and SSO need the custom-priced Enterprise plan.
  • –A thin independent review record: no G2 reviews and 3.6 stars from 240 reviews on Google Play, and SOC 2 Type II and ISO 27001 are shown as engagements rather than completed certifications.

Technical Details

Deployment
webmobile
Model architectureOpenAI models deployed on Microsoft Azure AI Foundry for AI features (per Rayyan's subprocessor list), plus Rayyan's duplicate detection and relevance prediction
Avg setup timeFree sign-up with no credit card; no published setup time
Autonomous rateResearchPilot's AI Reviewer screens every article against the review's criteria as a team member and records a reason for each decision; the AI Analyzer only recommends decisions for reviewers to accept. On other plans, duplicate detection and relevance predictions assist human screeners, who make all decisions. No accuracy rate is published by Rayyan.
Integrations
RISBibTeXEndNotePubMedRayyan APIPython SDK
Security
GDPRHIPAA

Similar agents

Rating

3.7/ 5
★★★★★

Editorial score

How we score this →

Recognition

Listed 2026
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Industries

PharmaHealthcare

Built for

Enterprise

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