Causaly vs Iris.ai (2026)

Causaly

by Causaly

Iris.ai

by Iris.ai

Pros

• ✓Answers are grounded in Causaly's own biomedical knowledge graphs, with more than 500 million facts in Bio Graph, and every claim links to the highlighted source passage it rests on.
• ✓Documented outcomes at pharmaceutical scale: ProQR reported 5x productivity over PubMed for target identification, and a top-10 global life sciences company cut proposal time by 75% during a disease area transition.
• ✓Open beyond enterprise contracts: self-serve plans from $99 per month with a 14-day trial and no credit card, and enterprise access inside Microsoft 365 Copilot and Teams.

Limitations

• –Built for biomedical and life sciences evidence, so its sources and knowledge graphs add little for research outside that domain.
• –Self-serve plans are single-user with monthly allowances of 400 or 500 credits, the Team plan is not yet available, and enterprise features such as the Enterprise Data Fabric are priced through sales.
• –Customer Content is never used for model training, but customer queries and performance data may be used to develop and improve the software, with a no-training commitment on performance data for Team plan customers.

Pros

• ✓Covers the path from raw documents to governed knowledge for AI agents, with Axion for data preparation, Neuralith for knowledge graphs and RSpace for research.
• ✓Named customers span manufacturing, agriculture, publishing, research and government, including Mercedes-Benz, ArcelorMittal, Syngenta, USDA and the Max Planck Society.
• ✓Deploys through an API, on-premise or in the cloud, and states ISO 27001 certification and that client data is never used to train general models.

Limitations

• –Axion and Neuralith are sold through a demo request. Only the RSpace Individual Membership has a published price, at EUR 292 per month or EUR 3,500 per year.
• –No public API documentation or MCP server is published, and Axion and Neuralith deployments are scoped with Iris.ai's team rather than set up self-serve.
• –RSpace's cloud import accepts English-language documents only, up to 10,000 documents and 5 GB, and its trial moves to a paid period automatically after 10 days.